Copper is mainly excreted in the feces. Small amounts can also be eliminated in hair and nails. In one study, researchers found it takes 13 to 33 days for half of a large copper dose to be eliminated from the body. Whether copper sulfate causes cancer in animals is uncertain. The U. Environmental Protection Agency U. EPA has not published a cancer rating for copper sulfate.
This is due to a lack of evidence linking copper or copper salts to cancer development in animals that can normally regulate copper in their bodies. One study looked at long-term work-related exposures to copper sulfate. They found an increased risk of kidney cancer. Another study found that decreasing copper can inhibit cancer growth.
Animal studies have provided conflicting results. Studies in humans of long-term non-cancer effects to copper sulfate were not identified. However, Wilson's disease may provide insight into potential health effects over long periods of time.
Wilson's disease is a rare genetic disorder in which the body retains too much copper. The effects include infertility, higher miscarriage rates, loss of menses and hormonal imbalances in women. In men, the testes don't function properly. In one study, mice were fed very large amounts of copper sulfate before and during pregnancy. Some baby mice died during gestation or did not develop normally. Children may be especially sensitive to pesticides compared to adults. However, there are currently no data to conclude that children have increased sensitivity specifically to copper sulfate.
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