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Biochim Biophys Acta ; Iguchi K. Effect of bisphosphonates on anticancer activity in prostate cancer cells. Yakugaku Zasshi ; Aapro M, Saad F. How can antibiotics work against cancer? We take a look at anthracycline drugs. Experts say new blood tests may dramatically change cancer diagnostics, although more research is needed. The nonprofit, cloud-based network provides games, movies, STEM education, and other programs for children who are isolated with serious illnesses.
Health Conditions Discover Plan Connect. Medically reviewed by Yamini Ranchod, Ph. Types of cancer most likely to spread to the bones. Outlook once cancer has spread to the bones. Survival rates of bone metastases. Type of cancer Percent of cases that metastasize after 5 years 5-year survival rate after metastasis Prostate Treatment options if your cancer has metastasized.
What to do next. Online Multiple Sclerosis Support Groups. The Best Cancer Blogs of Bone Metastases. Read this next. Medically reviewed by Deborah Weatherspoon, Ph.
The Best Cancer Blogs of Here are the best cancer blogs to find support, gain information, learn about the newest research and treatments, and more. Medically reviewed by University of Illinois. Does Talcum Powder Cause Cancer?
Accessed March 8, Niederhuber JE, et al. Bone metastases. In: Abeloff's Clinical Oncology. Elsevier; Accessed Dec. Metastatic cancer. National Cancer Institute. Saravana-Bawan S, et al. Palliation of bone metastases—exploring options beyond radiotherapy. Find information on cancer that starts in the bone: Bone Cancer Find information on cancer that starts in the bone marrow: Multiple Myeloma.
Inside the spongy bone is your bone marrow. It contains stem cells that can develop into white blood cells, red blood cells, or platelets. The cells that make up the bones are always changing. Some cells, called osteoclasts Os-tee-oh-klasts , break down bone. Other cells, called osteoblasts Os-tee-oh-blasts , form new bone. Once cancer gets into your bones, it can keep these cells from working properly.
This can cause your bones to become thin and weak and increase your risk for bone breaks fractures. Your doctor may suggest you have a bone density test—called a DEXA scan. The test uses low levels of X-rays to measure how much calcium and minerals are in the bones in your hip, wrist, and spine.
The test is painless. The test results show if you have bone loss. This can be either:. Your FRAX score is an estimate of how likely you are to break a bone in the next 10 years. Your score is based on your age, weight, gender, smoking history, alcohol use, and whether you have already had one or more broken bones. Your doctor will use the scores from these two tests to decide whether to recommend that you take a bone building drug.
Bone metastases are one of the most common types of metastases. It is also very treatable. The treatments your doctor recommends will be based on:. Chemotherapy: Used to stop the growth of cancer cells that may be anywhere in your body, including in your bone.
Learn about chemotherapy. These therapies, taken as pills or injections, can help stop cancer cell growth in the bones and other parts of your body. The hormone therapies used to treat prostate cancer block testosterone. The hormone therapies used to treat breast cancer block estrogen. Bone Building Drugs: These drugs help strengthen bone, slow bone metastases, and help reduce pain caused by bone metastases. Often given by IV into the vein or as injections under the skin, they include:.
There are different types of bisphosphonates bis-FOS-foh-nayts available. The most common side effects are headache, muscle aches, and sometimes fever and chills for up to three days after the injection. In rare cases, after long-term use, patients have developed a crack in the middle of their thigh bone. Another rare complication is osteonecrosis bone death of the jaw often occurring after a dental procedure such as having a tooth pulled. For this reason, you should have a dental exam before starting on a bisphosphonate and periodically while on treatment.
You should also tell your dentist you are taking a bisphosphonate treatment for your cancer. Cancer cells can get bone cells to break down bone more quickly. Xgeva, which is given as an injection under the skin, can help stop this process.
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